My Tirzepatide Hair Loss Story — And How I Got My Hair Back
- Ashley Chaffee
- Dec 10, 2025
- 4 min read
My Hair Loss & Hair Gain Journey: What Actually Worked for Me
If you told me a few years ago that I’d be casually mixing peptides, vitamins, red light, mesotherapy, and scalp injections like some kind of DIY hair-science pharmacist… I’d probably believe you. But I wouldn’t have believed how wild the journey would get.
This is the story of how my hair thinned, how I spiraled, and how I slowly brought my hairline — especially my temples — back to life.
Where It Started: The Panic Era
My hair loss didn’t hit suddenly. It crept up quietly… until one day I caught the wrong angle in a photo and almost passed away.
Here’s what stacked against me all at once:
A super tight braid incident that caused major scalp soreness and shedding

The BRAID incident, I lost SO much hair Medication-induced hair loss from Tirzepatide
Stress
Thinning I didn’t notice until it was obvious
Suddenly I had widening part lines, see-through temples, and brittle zones I had never seen before. Once I understood the why, I finally knew how to tackle the fix.
And when I decided to fix it, I went all in.
Photos of the start of my hair loss journey
What I Did to Actually Regrow My Hair
No fluff. No influencer tricks. Just what worked for me.
1. Oral Minoxidil: The Silent Hero
I started oral minoxidil on February 16, 2025, and I wish I’d done it sooner.
What it did:
Reduced shedding within weeks
Gave me thicker ponytail density
Kick-started baby hairs at my temples
Improved overall coverage
My dose:
Started at 0.625 mg, then adjusted with my prescriber.
2. Spironolactone: Hormonal Support
Because hormones play a huge role in how my hair behaves, spironolactone helped stabilize everything.
What it improved:
Slowed down miniaturization
Reduced hormonal shedding
Helped prevent future thinning
BONUS: fewer hormonal breakouts
Dose:
12.5 mg for the first week → increased to 25 mg.
3. Supplements That Actually Helped
My supplement stack wasn’t “throw things at the wall,” it was targeted — and it made a difference.
• Marine collagen + biotin (Walmart hair supplement)
Strengthens new growth and improves strand texture.
• Zinc + Ashwagandha + Saw Palmetto
Supports hormonal balance and stress-related shedding.
• NAC, Magnesium Glycinate, Fish Oil
Helps with healthy hair growth and scalp circulation.
• Iron + Vitamin C
Critical if you run low-normal. Hair needs iron to grow.
• Vitamin A 10,000 IU
Supports thyroid conversion and scalp cell turnover.
• Saccharomyces boulardii + L-glutamine
Gut health = nutrient absorption = better hair growth.
4. Peptides: The Regrowth Accelerator
My peptide routine didn’t just help my energy and mood — it supported my scalp healing and hair growth too.
Selank
Helps with stress, which can absolutely worsen shedding.
MOTS-c + NAD+ + SS-31
Supports mitochondrial function → better recovery → healthier follicles.
Glow Peptide (GHK-Cu + BPC-157 + TB-500)
GHK-Cu is incredible for tissue repair and follicle support.
I track every dose, timing, energy level, and scalp response.
The Two Treatments That Changed Everything
Here’s where the real magic happened.
5. PRF: My Most Dramatic Regrowth
This was my biggest transformation — nothing worked faster or more noticeably than PRF.
Because I do my own PRF (RN perks), I saw improvements quickly and consistently.
What PRF did:
Woke up dormant follicles
Thickened those wispy, miniaturized hairs
Filled in the “see-through” temples
Gave me stronger, darker baby hairs
Reduced shedding during stress
The photos don’t lie — PRF was the treatment that made me go, “Okay… this is actually working.”
PRF is my foundation.
6. Exosomes + Mesotherapy (50+ Injections): The Perfect Booster
Exosomes weren’t the most dramatic on their own, but they were an amazing enhancer to everything else I was doing.
I don’t do microneedling for these — I do true mesotherapy with around 50–70 tiny scalp injections per session.
My routine:
Atlantis Hair Exosomes
Mesotherapy across temples, hairline, and crown
~50+ microinjections per session
Alternated with PRF cycles
Copper peptides on off days
What exosomes added:
Faster healing after PRF
More consistent density
A softer, healthier look to the new growth
Stronger response in thin areas over time
Exosomes kept the momentum going between PRF sessions.
7. Red Light Therapy
Red + near-infrared wavelengths helped support circulation and hair cycling.
Benefits I noticed:
Less shedding
Stronger hairs
Better density
More regrowth when combined with PRF/minoxidil
Consistency (3–4x per week) made all the difference.
Where My Hair Is Today
Right now, I have:
Short baby hairs on both temples
A fuller, tighter hairline
Darker, stronger regrowth
Less shedding
Better density in photos
Softer, healthier overall texture
LONGER EYELASHES (Seriously)
I’m finally out of the panic era and into the growth era.

If You’re Starting Your Own Hair Journey…
Here’s what I’d tell anyone:
Tirzepatide-related shedding can be reversed.
PRF is the most powerful scalp treatment I’ve used.
Minoxidil + spironolactone = a strong foundation.
Exosomes are an excellent booster.
Peptides support recovery and healing.
Supplements matter more than people admit.
Take progress photos — even when you don’t want to.
Consistency is the real secret.
IT TAKES TIME. GIVE IT ATLEAST SIX MONTHS TO NOTICE A DIFFERENCE.
Losing hair is emotional. Regrowing it is empowering. And I’m finally seeing the payoff from everything I’ve worked for.









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